Challenges & Advances in ALS Biomarker Development
At the 2026 Target ALS Annual Meeting, leading experts gathered for a candid roundtable discussion on the current state of biomarker development for ALS: what’s working, where the field is today, and what breakthroughs could change the trajectory of drug development and clinical trials. Topics covered include the promise and limitations of fluid-based biomarkers, the role of neurofilament and emerging candidates, challenges in clinical validation, and how the field can accelerate progress through collaboration and open science. Featuring: Toby Ferguson (Alnylam Pharmaceuticals and Target ALS Board Member), Danielle Graham (Biogen), Nicholas Ashton (Banner Health), Michael Benatar (University of Miami ALS Center)